解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The spatial location of an object can be represented in two frames of reference: egocentric (relative to the observer's body or body parts) and allocentric (relative to another object independent of the observer). The object positions relative to the two frames can be either congruent (e.g., both left or both right) o...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23508
更新日期:2017-04-01 00:00:00
abstract::There is substantial variability in speech recognition ability across patients with cochlear implants (CIs), auditory brainstem implants (ABIs), and auditory midbrain implants (AMIs). To better understand how this variability is related to central processing differences, the current electroencephalography (EEG) study ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23515
更新日期:2017-04-01 00:00:00
abstract::The dopaminergic system plays a key role in motor function and motor abnormalities have been shown to be a specific feature of psychosis. Due to their dopaminergic action, antipsychotic drugs may be expected to modulate motor function, but the precise effects of these drugs on motor function remain unclear. We carried...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.23485
更新日期:2017-04-01 00:00:00
abstract::Advances in functional brain imaging have improved the search for potential endophenotypic markers in schizophrenia. Here, we employed independent component analysis (ICA) and dynamic causal modeling (DCM) in resting state fMRI on a sample of 35 schizophrenia patients, 20 first-degree relatives and 35 control subjects...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23477
更新日期:2017-04-01 00:00:00
abstract::Multivariate functional connectivity analyses of neuroimaging data have revealed the importance of complex, distributed interactions between disparate yet interdependent brain regions. Recent work has shown that topological properties of functional brain networks are associated with individual and group differences in...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23518
更新日期:2017-04-01 00:00:00
abstract::Much of the literature exploring differences between intrinsic and task-evoked brain architectures has examined changes in functional connectivity patterns between specific brain regions. While informative, this approach overlooks important overall functional changes in hub organization and network topology that may p...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23500
更新日期:2017-04-01 00:00:00
abstract::Research in amyotrophic lateral sclerosis (ALS) suggests that executive dysfunction, a prevalent cognitive feature of the disease, is associated with abnormal structural connectivity and white matter integrity. In this exploratory study, we investigated the white matter constructs of executive dysfunction, and attempt...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23452
更新日期:2017-03-01 00:00:00
abstract::Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by progressive decline in memory and other aspects of cognitive function. Diffusion-weighted imaging (DWI) offers a non-invasive approach to delineate the effects of AD on white matter (WM) integrity. Previous studies calculated either some ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23448
更新日期:2017-03-01 00:00:00
abstract::The processes underlying perceptual decision making are diverse and typically engage a distributed network of brain areas. It is a particular challenge to establish a sensory-to-motor functional hierarchy in such networks. This is because single-cell recordings mainly study the nodes of decision networks in isolation ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23446
更新日期:2017-03-01 00:00:00
abstract::In social interactions, humans are expected to regulate interpersonal distance in response to the emotion displayed by others. Yet, the neural mechanisms implicated in approach-avoidance tendencies to distinct emotional expressions have not been fully described. Here, we investigated the neural systems implicated in r...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23467
更新日期:2017-03-01 00:00:00
abstract::Cognitive deficits are common in Parkinson's disease and we suspect that dysfunctions of connected brain regions can be the source of these deficits. The aim of the present study was to investigate changes in whole-brain intrinsic functional connectivity according to differences in cognitive profiles in Parkinson's di...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23474
更新日期:2017-03-01 00:00:00
abstract::Task-switching performance relies on a broadly distributed frontoparietal network and declines in older adults. In this study, they investigated whether this age-related decline in task switching performance was mediated by variability in global or regional white matter microstructural health. Seventy cognitively inta...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23473
更新日期:2017-03-01 00:00:00
abstract::Low frequency theta band oscillations (4-8 Hz) are thought to provide a timing mechanism for hippocampal place cell firing and to mediate the formation of spatial memory. In rodents, hippocampal theta has been shown to play an important role in encoding a new environment during spatial navigation, but a similar functi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23458
更新日期:2017-03-01 00:00:00
abstract::Altered serotonergic neurotransmission has been found to cause impulsive and aggressive behavior, as well as increased motor activity, all exemplifying key symptoms of ADHD. The main objectives of this positron emission tomography (PET) study were to investigate the serotonin transporter binding potential (SERT BPND )...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23418
更新日期:2017-02-01 00:00:00
abstract::Prenatal alcohol exposure (PAE) can cause central nervous system dysfunction and widespread structural anomalies as detected by magnetic resonance imaging (MRI). This study focused on diffusion tensor imaging (DTI) of white matter in a large sample of PAE participants that allowed us to examine correlations with behav...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23371
更新日期:2017-01-01 00:00:00
abstract::Neurodegenerative diseases such as Alzheimer's disease (AD) have been recognized to exhibit disease-specific brain vulnerability patterns. Apolipoprotein E (APOE) ɛ4 allele imparts a high genetic risk of developing AD. Whether the APOE ɛ4 allele damages the brain when cognitive functions are still intact is important ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23359
更新日期:2017-01-01 00:00:00
abstract::Subcortical functions for language capacities are poorly defined, but may be investigated in the context of deep brain stimulation. Here, we studied event-related potentials recorded from electrodes in the subthalamic nucleus (STN) and the thalamic ventral intermediate nucleus (VIM) together with surface-EEG. Particip...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23366
更新日期:2017-01-01 00:00:00
abstract::Dysfunction of corticostriatal loops has been proposed to underlie certain cognitive and behavioral problems associated with various neuropsychiatric disorders, such as obsessive-compulsive disorder (OCD) characterized by repetitive, unwanted thoughts, and behaviors. Although functional abnormalities in the loops invo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23347
更新日期:2017-01-01 00:00:00
abstract::Free water elimination (FWE) in brain diffusion MRI has been shown to improve tissue specificity in human white matter characterization both in health and in disease. Relative to the classical diffusion tensor imaging (DTI) model, FWE is also expected to increase sensitivity to microstructural changes in longitudinal ...
journal_title:Human brain mapping
pub_type: 杂志文章,多中心研究
doi:10.1002/hbm.23350
更新日期:2017-01-01 00:00:00
abstract::Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity in brain activity between different regions. SC is typically indexed by measures of white m...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23403
更新日期:2017-01-01 00:00:00
abstract::Current neuroscientific research has shown that the brain reconfigures its functional interactions at multiple timescales. Here, we sought to link transient changes in functional brain networks to individual differences in behavioral and cognitive performance by using an active learning paradigm. Participants learned ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23285
更新日期:2016-11-01 00:00:00
abstract::The nuclei of the human amygdala remain difficult to distinguish in individual subject structural magnetic resonance images. However, interpretation of the amygdala's role in whole brain networks requires accurate localization of functional activity to a particular nucleus or subgroup of nuclei. To address this, high ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23289
更新日期:2016-11-01 00:00:00
abstract::The influential competition between verbal and implicit systems (COVIS) model proposes that category learning is driven by two competing neural systems-an explicit, verbal, system, and a procedural-based, implicit, system. In the current fMRI study, participants learned either a conjunctive, rule-based (RB), category ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23259
更新日期:2016-10-01 00:00:00
abstract::Behavioral evidence and theory suggest gesture and language processing may be part of a shared cognitive system for communication. While much research demonstrates both gesture and language recruit regions along perisylvian cortex, relatively less work has tested functional segregation within these regions on an indiv...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23251
更新日期:2016-10-01 00:00:00
abstract::The functional organization of the human brain consists of a high degree of connectivity between interhemispheric homologous regions. The degree of homotopic organization is known to vary across the cortex and homotopic connectivity is high in regions that share cross-hemisphere structural connections or are activated...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23214
更新日期:2016-08-01 00:00:00
abstract::Fetal alcohol spectrum disorders comprise the spectrum of cognitive, behavioral, and neurological impairments caused by prenatal alcohol exposure (PAE). Diffusion tensor imaging (DTI) was performed on 54 children (age 10.1 ± 1.0 years) from the Cape Town Longitudinal Cohort, for whom detailed drinking histories obtain...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23218
更新日期:2016-08-01 00:00:00
abstract::Rasagiline is a monoamine oxidase type B inhibitor that possesses no amphetamine-like properties, and provides symptomatic relief in early and late stages of Parkinson's disease (PD). Data in animal models of PD suggest that chronic administration of rasagiline is associated with structural changes in the substantia n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23213
更新日期:2016-08-01 00:00:00
abstract::Fast cancellation or switching of action plans is a critical cognitive function. Rapid signal transmission is key for quickly executing and inhibiting responses, and the structural integrity of connections between brain regions plays a crucial role in signal transmission speed. In this study, we used the search-step t...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23209
更新日期:2016-08-01 00:00:00
abstract::The question of how spatially organized activity in the visual cortex behaves during eyes-closed, lysergic acid diethylamide (LSD)-induced "psychedelic imagery" (e.g., visions of geometric patterns and more complex phenomena) has never been empirically addressed, although it has been proposed that under psychedelics, ...
journal_title:Human brain mapping
pub_type: 临床试验,杂志文章
doi:10.1002/hbm.23224
更新日期:2016-08-01 00:00:00
abstract::Central brain network connections greatly contribute to overall network efficiency. Here we examined whether small vessel disease (SVD) related white matter alterations in central brain network connections have a greater impact on executive functioning than alterations in non-central brain network connections. Brain n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23186
更新日期:2016-07-01 00:00:00
abstract::Infants born prematurely are at increased risk of adverse neurodevelopmental outcome. The measurement of white matter tissue composition and structure can help predict functional performance. Specifically, measurements of myelination and indicators of myelination status in the preterm brain could be predictive of late...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23188
更新日期:2016-07-01 00:00:00
abstract::Catechol-O-methyltransferase (COMT), located on chromosome 22q11.2, encodes an enzyme critical for dopamine flux in the prefrontal cortex. Genetic variants of COMT have been suggested to functionally manipulate prefrontal morphology and function in healthy adults. This study aims to investigate modulative roles of ind...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23161
更新日期:2016-06-01 00:00:00
abstract::Studies have found non-negligible differences in cortical thickness estimates across versions of software that are used for processing and quantifying MRI-based cortical measurements, and issues have arisen regarding these differences, as obtained estimates could potentially affect the validity of the results. However...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23139
更新日期:2016-05-01 00:00:00
abstract::Dynamic functional brain connectivity analysis is a fast expanding field in computational neuroscience research with the promise of elucidating brain network interactions. Sliding temporal window based approaches are commonly used in order to explore dynamic behavior of brain networks in task-free functional magnetic ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23151
更新日期:2016-05-01 00:00:00
abstract::There are an increasing number of neuroimaging studies that allow a better understanding of symptoms, neural correlates and associated conditions of fibromyalgia. However, the results of these studies are difficult to compare, as they include a heterogeneous group of patients, use different stimulation paradigms, task...
journal_title:Human brain mapping
pub_type: 杂志文章,meta分析
doi:10.1002/hbm.23132
更新日期:2016-05-01 00:00:00
abstract::Dopaminergic degeneration is a hallmark of Parkinson's disease (PD), which causes various symptoms affected by corticostriatal circuits. So far, the relationship between cortical changes and dopamine loss in the striatum is unclear. Here, we evaluate the gray matter (GM) changes in accordance with striatal dopaminergi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23130
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To assess the structural correlates of cognitive and behavioral impairment in motor neuron diseases (MND) using multimodal MRI. METHODS:One hundred one patients with sporadic MND (56 classic amyotrophic lateral sclerosis, 31 upper motor neuron phenotype, and 14 lower motor neuron phenotype) and 51 controls w...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23124
更新日期:2016-04-01 00:00:00
abstract::We investigated the role of the dopamine system [i.e., subcortical-medial prefrontal cortex (mPFC) network] in dreaming, by studying patients with Parkinson's Disease (PD) as a model of altered dopaminergic transmission. Subcortical volumes and cortical thickness were extracted by 3T-MR images of 27 PD patients and 27...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23095
更新日期:2016-03-01 00:00:00
abstract::The theory of material specific lateralization of memory function posits that left and right MTL regions are asymmetrically involved in mnemonic processing of verbal and nonverbal material respectively. Lesion and functional imaging (fMRI) studies provide robust evidence for a left MTL asymmetry in the verbal memory d...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23077
更新日期:2016-03-01 00:00:00
abstract::Posttraumatic stress disorder (PTSD) is a prevalent, debilitating, and difficult to treat psychiatric disorder. Very little is known of how PTSD affects neuroplasticity in the developing adolescent brain. Whereas multiple lines of research implicate amygdala-centered network dysfunction in the pathophysiology of adult...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23093
更新日期:2016-03-01 00:00:00